Hemolysis in patients w/ G6PD deficiency (after large doses); delayed-type allergic response; insomnia, sleepiness; headache; flushing; abdominal cramps, diarrhea (at ≥1 g daily), flatulent distention, gastric discomfort, heartburn, nausea, transient colic, vomiting; increased urination, kidney stone formation in patients w/ preexisting renal disease (w/ large doses); fatigue; acidification of urine, precipitation of urate, cystine, or oxalate stones, or drugs in the urinary tract, decreased blood pH; erosion of dental enamel.